HCSGD entry for TAF6
1. General information
| Official gene symbol | TAF6 |
|---|---|
| Entrez ID | 6878 |
| Gene full name | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa |
| Other gene symbols | MGC:8964 TAF(II)70 TAF(II)80 TAF2E TAFII-70 TAFII-80 TAFII70 TAFII80 TAFII85 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005669 | Transcription factor TFIID complex | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006352 | DNA-templated transcription, initiation | IDA IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | NAS TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0033276 | Transcription factor TFTC complex | IDA | cellular_component |
| GO:0045786 | Negative regulation of cell cycle | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0051090 | Regulation of sequence-specific DNA binding transcription factor activity | IEA | biological_process |
| GO:0071339 | MLL1 complex | IDA | cellular_component |
| GO:2001141 | Regulation of RNA biosynthetic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7648215797 | 0.1071434710 | 0.9999902473 | 0.6264156597 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2343483016 |
| GSE13712_SHEAR | Down | -0.5522895617 |
| GSE13712_STATIC | Down | -0.1388011611 |
| GSE19018 | Down | -0.1462370212 |
| GSE19899_A1 | Down | -0.5134325923 |
| GSE19899_A2 | Down | -0.0591504976 |
| PubMed_21979375_A1 | Up | 0.3895785756 |
| PubMed_21979375_A2 | Down | -0.2692467093 |
| GSE35957 | Down | -0.4767333243 |
| GSE36640 | Down | -0.4984587881 |
| GSE54402 | Up | 0.1023761112 |
| GSE9593 | Down | -0.3596994248 |
| GSE43922 | Down | -0.1829780986 |
| GSE24585 | Up | 0.2559626681 |
| GSE37065 | Down | -0.2158945981 |
| GSE28863_A1 | Up | 0.2348999807 |
| GSE28863_A2 | Up | 0.3899096575 |
| GSE28863_A3 | Up | 0.4039515843 |
| GSE28863_A4 | Down | -0.0982362392 |
| GSE48662 | Up | 0.3142254200 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-5p | MIMAT0000093 | MIRT028133 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040207 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
