HCSGD entry for TAF5
1. General information
| Official gene symbol | TAF5 |
|---|---|
| Entrez ID | 6877 |
| Gene full name | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| Other gene symbols | TAF2D TAFII100 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA IMP | molecular_function |
| GO:0004402 | Histone acetyltransferase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005669 | Transcription factor TFIID complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006352 | DNA-templated transcription, initiation | IDA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016568 | Chromatin modification | IC | biological_process |
| GO:0016573 | Histone acetylation | IDA | biological_process |
| GO:0033276 | Transcription factor TFTC complex | IDA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0044212 | Transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0046983 | Protein dimerization activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6222571749 | 0.0127875423 | 0.9999902473 | 0.2233449900 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1792743617 |
| GSE13712_SHEAR | Down | -0.4678520111 |
| GSE13712_STATIC | Down | -0.2361993130 |
| GSE19018 | Down | -0.6292099210 |
| GSE19899_A1 | Up | 0.0200058846 |
| GSE19899_A2 | Down | -0.8623098016 |
| PubMed_21979375_A1 | Down | -0.2740455318 |
| PubMed_21979375_A2 | Down | -1.0794548274 |
| GSE35957 | Down | -1.1474418047 |
| GSE36640 | Down | -2.0352737915 |
| GSE54402 | Up | 0.3717043450 |
| GSE9593 | Down | -0.9257697606 |
| GSE43922 | Up | 0.3414526735 |
| GSE24585 | Up | 0.3055399591 |
| GSE37065 | Down | -0.1723380383 |
| GSE28863_A1 | Up | 0.2895801972 |
| GSE28863_A2 | Up | 0.6324612936 |
| GSE28863_A3 | Down | -0.5647947272 |
| GSE28863_A4 | Up | 0.3088041454 |
| GSE48662 | Down | -0.3930369642 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027509 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030707 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051848 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052580 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
