HCSGD entry for SYT4
1. General information
| Official gene symbol | SYT4 |
|---|---|
| Entrez ID | 6860 |
| Gene full name | synaptotagmin IV |
| Other gene symbols | HsT1192 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000149 | SNARE binding | IEA | molecular_function |
| GO:0001786 | Phosphatidylserine binding | IEA | molecular_function |
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0007269 | Neurotransmitter secretion | IEA | biological_process |
| GO:0008021 | Synaptic vesicle | IEA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030276 | Clathrin binding | IEA | molecular_function |
| GO:0030672 | Synaptic vesicle membrane | IEA | cellular_component |
| GO:0031045 | Dense core granule | IEA | cellular_component |
| GO:0031339 | Negative regulation of vesicle fusion | IEA | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0045955 | Negative regulation of calcium ion-dependent exocytosis | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6590216215 | 0.7346657954 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0221231611 |
| GSE13712_SHEAR | Up | 0.1603304789 |
| GSE13712_STATIC | Down | -0.1801778272 |
| GSE19018 | Up | 0.1139106390 |
| GSE19899_A1 | Up | 0.0645902103 |
| GSE19899_A2 | Down | -0.0538609845 |
| PubMed_21979375_A1 | Up | 0.1375791954 |
| PubMed_21979375_A2 | Down | -0.2674669748 |
| GSE35957 | Up | 0.1990857350 |
| GSE36640 | Up | 0.1118054661 |
| GSE54402 | Down | -0.0468467609 |
| GSE9593 | Up | 0.1000826992 |
| GSE43922 | Up | 0.0137633389 |
| GSE24585 | Down | -0.0111509680 |
| GSE37065 | Up | 0.0008655220 |
| GSE28863_A1 | Up | 0.0016762205 |
| GSE28863_A2 | Up | 0.0012381842 |
| GSE28863_A3 | Up | 0.1285361263 |
| GSE28863_A4 | Up | 0.0018109780 |
| GSE48662 | Up | 0.0769885147 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020421 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-142-3p | MIMAT0000434 | MIRT021609 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-let-7b-3p | MIMAT0004482 | MIRT038996 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
