HCSGD entry for SYP


1. General information

Official gene symbolSYP
Entrez ID6855
Gene full namesynaptophysin
Other gene symbolsMRXSYP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0006897EndocytosisIEA ISSbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0015485Cholesterol bindingIDAmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016188Synaptic vesicle maturationNASbiological_process
GO:0017075Syntaxin-1 bindingIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030285Integral component of synaptic vesicle membraneNAScellular_component
GO:0030672Synaptic vesicle membraneIEAcellular_component
GO:0032403Protein complex bindingIEAmolecular_function
GO:0042169SH2 domain bindingIEAmolecular_function
GO:0042734Presynaptic membraneIEAcellular_component
GO:0042802Identical protein bindingIEAmolecular_function
GO:0043234Protein complexIEAcellular_component
GO:0044306Neuron projection terminusIEAcellular_component
GO:0048169Regulation of long-term neuronal synaptic plasticityIEA ISSbiological_process
GO:0048172Regulation of short-term neuronal synaptic plasticityIEA ISSbiological_process
GO:0048499Synaptic vesicle membrane organizationNASbiological_process
GO:0048786Presynaptic active zoneIEAcellular_component
GO:0060076Excitatory synapseIEAcellular_component
GO:0071310Cellular response to organic substanceIEAbiological_process
GO:2000474Regulation of opioid receptor signaling pathwayIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39465480790.90570032670.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0359188133
GSE13712_SHEARDown-0.2134940003
GSE13712_STATICUp0.0880058061
GSE19018Up0.2027034048
GSE19899_A1Up0.0530013706
GSE19899_A2Up0.0432096284
PubMed_21979375_A1Up0.1029112598
PubMed_21979375_A2Down-0.0162677316
GSE35957Up0.1260601526
GSE36640Up0.0906432643
GSE54402Up0.3249437660
GSE9593Up0.0000681541
GSE43922Up0.1265374778
GSE24585Down-0.1436167674
GSE37065Up0.1134446337
GSE28863_A1Down-0.0186675756
GSE28863_A2Down-0.0646016314
GSE28863_A3Up0.4510739700
GSE28863_A4Down-0.0262786324
GSE48662Down-0.0449815497

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017945MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.