HCSGD entry for SYP
1. General information
Official gene symbol | SYP |
---|---|
Entrez ID | 6855 |
Gene full name | synaptophysin |
Other gene symbols | MRXSYP |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0005215 | Transporter activity | IEA | molecular_function |
GO:0006897 | Endocytosis | IEA ISS | biological_process |
GO:0008021 | Synaptic vesicle | IEA | cellular_component |
GO:0015485 | Cholesterol binding | IDA | molecular_function |
GO:0016020 | Membrane | IEA | cellular_component |
GO:0016021 | Integral component of membrane | IEA | cellular_component |
GO:0016188 | Synaptic vesicle maturation | NAS | biological_process |
GO:0017075 | Syntaxin-1 binding | IEA | molecular_function |
GO:0030054 | Cell junction | IEA | cellular_component |
GO:0030285 | Integral component of synaptic vesicle membrane | NAS | cellular_component |
GO:0030672 | Synaptic vesicle membrane | IEA | cellular_component |
GO:0032403 | Protein complex binding | IEA | molecular_function |
GO:0042169 | SH2 domain binding | IEA | molecular_function |
GO:0042734 | Presynaptic membrane | IEA | cellular_component |
GO:0042802 | Identical protein binding | IEA | molecular_function |
GO:0043234 | Protein complex | IEA | cellular_component |
GO:0044306 | Neuron projection terminus | IEA | cellular_component |
GO:0048169 | Regulation of long-term neuronal synaptic plasticity | IEA ISS | biological_process |
GO:0048172 | Regulation of short-term neuronal synaptic plasticity | IEA ISS | biological_process |
GO:0048499 | Synaptic vesicle membrane organization | NAS | biological_process |
GO:0048786 | Presynaptic active zone | IEA | cellular_component |
GO:0060076 | Excitatory synapse | IEA | cellular_component |
GO:0071310 | Cellular response to organic substance | IEA | biological_process |
GO:2000474 | Regulation of opioid receptor signaling pathway | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.3946548079 | 0.9057003267 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.0359188133 |
GSE13712_SHEAR | Down | -0.2134940003 |
GSE13712_STATIC | Up | 0.0880058061 |
GSE19018 | Up | 0.2027034048 |
GSE19899_A1 | Up | 0.0530013706 |
GSE19899_A2 | Up | 0.0432096284 |
PubMed_21979375_A1 | Up | 0.1029112598 |
PubMed_21979375_A2 | Down | -0.0162677316 |
GSE35957 | Up | 0.1260601526 |
GSE36640 | Up | 0.0906432643 |
GSE54402 | Up | 0.3249437660 |
GSE9593 | Up | 0.0000681541 |
GSE43922 | Up | 0.1265374778 |
GSE24585 | Down | -0.1436167674 |
GSE37065 | Up | 0.1134446337 |
GSE28863_A1 | Down | -0.0186675756 |
GSE28863_A2 | Down | -0.0646016314 |
GSE28863_A3 | Up | 0.4510739700 |
GSE28863_A4 | Down | -0.0262786324 |
GSE48662 | Down | -0.0449815497 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-335-5p | MIMAT0000765 | MIRT017945 | Microarray | Functional MTI (Weak) | 18185580 |
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