HCSGD entry for SYN1


1. General information

Official gene symbolSYN1
Entrez ID6853
Gene full namesynapsin I
Other gene symbolsSYN1a SYN1b SYNI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0003824Catalytic activityIEAmolecular_function
GO:0005215Transporter activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionIEAbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0048306Calcium-dependent protein bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18600514040.97364956500.84182919461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0354469463
GSE13712_SHEARUp0.1736508714
GSE13712_STATICUp0.0099353714
GSE19018Up0.0326737548
GSE19899_A1Up0.1296772696
GSE19899_A2Up0.1431630789
PubMed_21979375_A1Down-0.0799085331
PubMed_21979375_A2Up0.3042595416
GSE35957Down-0.0137042689
GSE36640Down-0.1697464255
GSE54402Up0.2816610947
GSE9593Up0.0212453514
GSE43922Up0.1177786050
GSE24585Up0.1169805180
GSE37065Down-0.0872576085
GSE28863_A1Down-0.0162369115
GSE28863_A2Up0.1840463745
GSE28863_A3Up0.3401306983
GSE28863_A4Up0.0884342877
GSE48662Up0.5246372051

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Adenosine-5'-Diphosphate MonothiophosphateDB01660 EXPT02847

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018882MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

18358537An OBGF400 neuronal phenotype was indicated by the recognition of a transfected neuronal progenitor-cell-specific tubulin-alpha1 gene promoter, intracellular presence of early neuronal markers (TuJ1, neuregulin-1, doublecortin and SOX2) and enhanced expression of neuronal- and progenitor lineage-active genes (MAP2, nestin, ENO and Syn1) compared to that of porcine epithelial cells
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