HCSGD entry for MED22
1. General information
| Official gene symbol | MED22 |
|---|---|
| Entrez ID | 6837 |
| Gene full name | mediator complex subunit 22 |
| Other gene symbols | MED24 SURF5 surf-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0016592 | Mediator complex | IDA IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6215370541 | 0.0223395122 | 0.9999902473 | 0.2871085449 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0519696322 |
| GSE13712_SHEAR | Down | -0.3085734694 |
| GSE13712_STATIC | Down | -0.2052067005 |
| GSE19018 | Down | -0.2871775853 |
| GSE19899_A1 | Down | -0.3288952766 |
| GSE19899_A2 | Down | -0.7562147899 |
| PubMed_21979375_A1 | Up | 0.5348200172 |
| PubMed_21979375_A2 | Up | 0.2692988602 |
| GSE35957 | Down | -0.4391717305 |
| GSE36640 | Down | -0.3437522819 |
| GSE54402 | Down | -0.0696696369 |
| GSE9593 | Down | -0.1107938640 |
| GSE43922 | Up | 0.0414877298 |
| GSE24585 | Down | -0.1104378331 |
| GSE37065 | Down | -0.1679865353 |
| GSE28863_A1 | Down | -1.0334212012 |
| GSE28863_A2 | Down | -0.3424567372 |
| GSE28863_A3 | Up | 0.8189687818 |
| GSE28863_A4 | Up | 0.1608727329 |
| GSE48662 | Down | -0.2984763010 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024383 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026109 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028841 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030376 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039340 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043298 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045399 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
