HCSGD entry for ABCC8
1. General information
| Official gene symbol | ABCC8 |
|---|---|
| Entrez ID | 6833 |
| Gene full name | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| Other gene symbols | ABC36 HHF1 HI HRINS MRP8 PHHI SUR SUR1 SUR1delta2 TNDM2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | NAS | biological_process |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006813 | Potassium ion transport | IEA TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IDA | cellular_component |
| GO:0008281 | Sulfonylurea receptor activity | IEA | molecular_function |
| GO:0015079 | Potassium ion transmembrane transporter activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0044325 | Ion channel binding | IPI | molecular_function |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0071805 | Potassium ion transmembrane transport | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5771129706 | 0.9232032788 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0020544724 |
| GSE13712_SHEAR | Down | -0.0647568321 |
| GSE13712_STATIC | Up | 0.1742108318 |
| GSE19018 | Up | 0.0736083806 |
| GSE19899_A1 | Up | 0.1018857816 |
| GSE19899_A2 | Down | -0.0410090231 |
| PubMed_21979375_A1 | Up | 0.1031175764 |
| PubMed_21979375_A2 | Down | -0.1088442484 |
| GSE35957 | Up | 0.1548375296 |
| GSE36640 | Down | -0.0120160738 |
| GSE54402 | Down | -0.0343611614 |
| GSE9593 | Up | 0.0354300399 |
| GSE43922 | Up | 0.0253115524 |
| GSE24585 | Up | 0.1620836353 |
| GSE37065 | Down | -0.0518818346 |
| GSE28863_A1 | Down | -0.0352068782 |
| GSE28863_A2 | Up | 0.0210196790 |
| GSE28863_A3 | Up | 0.2963649584 |
| GSE28863_A4 | Up | 0.1459988555 |
| GSE48662 | Up | 0.0368368873 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Adenosine triphosphate | DB00171 | NUTR00017 | EXPT00007 |
| Glimepiride | DB00222 | APRD00381 |
| Nateglinide | DB00731 | APRD00593 |
| Repaglinide | DB00912 | APRD00439 |
| Gliclazide | DB01120 | APRD00460 |
| Gliquidone | DB01251 | - |
| Mitiglinide | DB01252 | - |
| Glycodiazine | DB01382 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018447 | Microarray | Functional MTI (Weak) | 18185580 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
