HCSGD entry for SULT2A1
1. General information
| Official gene symbol | SULT2A1 |
|---|---|
| Entrez ID | 6822 |
| Gene full name | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| Other gene symbols | DHEA-ST DHEAS HST ST2 ST2A1 ST2A3 STD hSTa |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0007586 | Digestion | NAS | biological_process |
| GO:0008146 | Sulfotransferase activity | IDA TAS | molecular_function |
| GO:0008202 | Steroid metabolic process | TAS | biological_process |
| GO:0030573 | Bile acid catabolic process | IEA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047704 | Bile-salt sulfotransferase activity | IEA | molecular_function |
| GO:0050427 | 3'-phosphoadenosine 5'-phosphosulfate metabolic process | TAS | biological_process |
| GO:0051923 | Sulfation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2858724023 | 0.9466006155 | 0.9853536467 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1871289198 |
| GSE13712_SHEAR | Up | 0.0752582201 |
| GSE13712_STATIC | Down | -0.1715382186 |
| GSE19018 | Up | 0.1868638990 |
| GSE19899_A1 | Up | 0.1141739176 |
| GSE19899_A2 | Up | 0.0278583360 |
| PubMed_21979375_A1 | Up | 0.0615909244 |
| PubMed_21979375_A2 | Up | 0.0511022189 |
| GSE35957 | Up | 0.0855145545 |
| GSE36640 | Up | 0.0552042612 |
| GSE54402 | Down | -0.0569060526 |
| GSE9593 | Down | -0.1082496439 |
| GSE43922 | Up | 0.0447238885 |
| GSE24585 | Up | 0.5132379311 |
| GSE37065 | Up | 0.0868881549 |
| GSE28863_A1 | Down | -0.0692965724 |
| GSE28863_A2 | Up | 0.0312065121 |
| GSE28863_A3 | Up | 0.2038811221 |
| GSE28863_A4 | Up | 0.1027752402 |
| GSE48662 | Down | -0.0080855689 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Dehydroepiandrosterone | DB01708 | EXPT00519 | DB06593 |
| Adenosine-3'-5'-Diphosphate | DB01812 | EXPT00370 |
| Aetiocholanolone | DB02854 | EXPT00443 |
| Mercury Diiodide | DB04445 | EXPT01740 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017405 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030437 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25343365 | 3) with values for two anabolic hormones (serum dehydroepiandrosterone sulfate [DHEAS] and insulin growth factor [IGF]-1), four catabolic hormones (cortisol, epinephrine, norepinephrine, and interleukin-6 [IL-6]), and LTL were examined |
| 25343365 | Neither DHEAS/cortisol nor IGF-1/cortisol ratio was associated with telomere length; however, a high A/C imbalance summary score was associated with greater odds of having a short LTL relative to long LTL (OR 1 |
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