HCSGD entry for STXBP3
1. General information
| Official gene symbol | STXBP3 |
|---|---|
| Entrez ID | 6814 |
| Gene full name | syntaxin binding protein 3 |
| Other gene symbols | MUNC18-3 MUNC18C PSP UNC-18C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006904 | Vesicle docking involved in exocytosis | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0017075 | Syntaxin-1 binding | IEA | molecular_function |
| GO:0019905 | Syntaxin binding | IPI | molecular_function |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0031091 | Platelet alpha granule | IDA | cellular_component |
| GO:0042581 | Specific granule | IDA | cellular_component |
| GO:0043312 | Neutrophil degranulation | IEP | biological_process |
| GO:0045955 | Negative regulation of calcium ion-dependent exocytosis | IMP | biological_process |
| GO:0051291 | Protein heterooligomerization | IEA | biological_process |
| GO:0070527 | Platelet aggregation | IMP | biological_process |
| GO:0070820 | Tertiary granule | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0800642263 | 0.8679700847 | 0.5961444130 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0947933987 |
| GSE13712_SHEAR | Up | 0.1165332564 |
| GSE13712_STATIC | Down | -0.0127698176 |
| GSE19018 | Up | 0.4141723510 |
| GSE19899_A1 | Up | 0.3321595900 |
| GSE19899_A2 | Up | 0.3238683456 |
| PubMed_21979375_A1 | Up | 0.4208291006 |
| PubMed_21979375_A2 | Up | 0.1575004056 |
| GSE35957 | Down | -0.0920186608 |
| GSE36640 | Up | 0.4749030994 |
| GSE54402 | Down | -0.2244235985 |
| GSE9593 | Up | 0.1473898870 |
| GSE43922 | Up | 0.1408212736 |
| GSE24585 | Up | 0.4088590986 |
| GSE37065 | Up | 0.2607019901 |
| GSE28863_A1 | Up | 0.0195507793 |
| GSE28863_A2 | Up | 0.4810310111 |
| GSE28863_A3 | Down | -0.6980780713 |
| GSE28863_A4 | Down | -0.2448415416 |
| GSE48662 | Down | -0.3480276884 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023896 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029784 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031842 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043953 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
