HCSGD entry for AURKC

1. General information

Official gene symbolAURKC
Entrez ID6795
Gene full nameaurora kinase C
Other gene symbolsAIE2 AIK3 ARK3 AurC SPGF5 STK13 aurora-C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000775Chromosome, centromeric regionIEAcellular_component
GO:0000793Condensed chromosomeIDAcellular_component
GO:0000910CytokinesisTASbiological_process
GO:0004672Protein kinase activityIDA IEAmolecular_function
GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0004712Protein serine/threonine/tyrosine kinase activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005819SpindleTAScellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0007126MeiosisIEAbiological_process
GO:0008608Attachment of spindle microtubules to kinetochoreTASbiological_process
GO:0016570Histone modificationTASbiological_process
GO:0030496MidbodyIDA TAScellular_component
GO:0032133Chromosome passenger complexTAScellular_component
GO:0032467Positive regulation of cytokinesisTASbiological_process
GO:0051233Spindle midzoneIDAcellular_component
GO:0051256Spindle midzone assembly involved in mitosisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47697045330.88312523840.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0163043561
GSE13712_SHEARDown-0.0371135911
GSE13712_STATICDown-0.2241507863
GSE19018Up0.2325598859
GSE19899_A1Up0.1893766174
GSE19899_A2Up0.0450838641
PubMed_21979375_A1Up0.4782073322
PubMed_21979375_A2Up0.1653078890
GSE35957Down-0.0516644843
GSE36640Down-0.0743603358
GSE54402Up0.1704795413
GSE9593Down-0.1578341162
GSE43922Up0.0375687241
GSE24585Down-0.1311691869
GSE37065Up0.0568493376
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1694187424

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.