HCSGD entry for STK10

1. General information

Official gene symbolSTK10
Entrez ID6793
Gene full nameserine/threonine kinase 10
Other gene symbolsLOK PRO2729
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0004702Receptor signaling protein serine/threonine kinase activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007165Signal transductionIBA TASbiological_process
GO:0023014Signal transduction by phosphorylationIBA TASbiological_process
GO:0035556Intracellular signal transductionIBA TASbiological_process
GO:0042801Polo kinase kinase activityTASmolecular_function
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0071593Lymphocyte aggregationIEAbiological_process
GO:2000401Regulation of lymphocyte migrationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01277807830.97710977170.28239445841.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1205515056
GSE13712_SHEARUp0.7228487856
GSE13712_STATICUp0.3251316016
GSE19018Up0.0424120623
GSE19899_A1Up0.1914347461
GSE19899_A2Up0.8612002533
PubMed_21979375_A1Up1.4366351268
PubMed_21979375_A2Up1.5650706540
GSE35957Down-0.2863964654
GSE36640Up0.3479711399
GSE54402Up0.4914498205
GSE9593Down-0.0072815578
GSE43922Up0.4339582740
GSE24585Up0.5507093284
GSE37065Down-0.0380438444
GSE28863_A1Down-0.0110104402
GSE28863_A2Up0.2210442374
GSE28863_A3Up0.1276024895
GSE28863_A4Down-0.0374021487
GSE48662Down-0.1429388822

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042193CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.