HCSGD entry for CDKL5

1. General information

Official gene symbolCDKL5
Entrez ID6792
Gene full namecyclin-dependent kinase-like 5
Other gene symbolsEIEE2 ISSX STK9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001764Neuron migrationISSbiological_process
GO:0004672Protein kinase activityIDAmolecular_function
GO:0004674Protein serine/threonine kinase activityTASmolecular_function
GO:0004693Cyclin-dependent protein serine/threonine kinase activityIEAmolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0016301Kinase activityIDAmolecular_function
GO:0032587Ruffle membraneISScellular_component
GO:0032839Dendrite cytoplasmISScellular_component
GO:0032855Positive regulation of Rac GTPase activityISSbiological_process
GO:0044294Dendritic growth coneISScellular_component
GO:0045773Positive regulation of axon extensionISSbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0048365Rac GTPase bindingISSmolecular_function
GO:0050773Regulation of dendrite developmentISSbiological_process
GO:0050775Positive regulation of dendrite morphogenesisISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91535505870.14050938790.99999024730.7210983048

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0607827164
GSE13712_SHEARUp0.0068256563
GSE13712_STATICUp0.0543980974
GSE19018Up0.2435296384
GSE19899_A1Up0.0385701849
GSE19899_A2Up0.0143483248
PubMed_21979375_A1Down-0.1246081726
PubMed_21979375_A2Down-0.0786004062
GSE35957Up0.1677912210
GSE36640Up0.0001801141
GSE54402Down-0.0006801941
GSE9593Down-0.0006552001
GSE43922Down-0.8677129728
GSE24585Down-0.1533262527
GSE37065Up0.0405303267
GSE28863_A1Down-0.3049949106
GSE28863_A2Down-0.5773073069
GSE28863_A3Up0.1589957336
GSE28863_A4Down-0.1283351336
GSE48662Down-0.3292057963

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-222-3pMIMAT0000279MIRT046657CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.