HCSGD entry for ELOVL4
1. General information
| Official gene symbol | ELOVL4 |
|---|---|
| Entrez ID | 6785 |
| Gene full name | ELOVL fatty acid elongase 4 |
| Other gene symbols | ADMD CT118 ISQMR STGD2 STGD3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006633 | Fatty acid biosynthetic process | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | NAS | biological_process |
| GO:0008020 | G-protein coupled photoreceptor activity | NAS | molecular_function |
| GO:0009584 | Detection of visible light | NAS | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0019367 | Fatty acid elongation, saturated fatty acid | IDA | biological_process |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0035338 | Long-chain fatty-acyl-CoA biosynthetic process | TAS | biological_process |
| GO:0042761 | Very long-chain fatty acid biosynthetic process | IDA ISS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3207696554 | 0.0177768170 | 0.9999902473 | 0.2611069196 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2963742597 |
| GSE13712_SHEAR | Down | -1.4365743327 |
| GSE13712_STATIC | Down | -0.4916868032 |
| GSE19018 | Down | -1.1149095322 |
| GSE19899_A1 | Up | 0.2480635771 |
| GSE19899_A2 | Up | 0.1095970390 |
| PubMed_21979375_A1 | Up | 0.7182331855 |
| PubMed_21979375_A2 | Down | -0.1257991894 |
| GSE35957 | Up | 0.1730447128 |
| GSE36640 | Up | 0.9762023791 |
| GSE54402 | Up | 1.0688653223 |
| GSE9593 | Up | 0.0570457102 |
| GSE43922 | Up | 0.0485636187 |
| GSE24585 | Up | 0.4061532377 |
| GSE37065 | Down | -0.0634342676 |
| GSE28863_A1 | Down | -0.3643710846 |
| GSE28863_A2 | Down | -0.2453784409 |
| GSE28863_A3 | Down | -0.8793065663 |
| GSE28863_A4 | Down | -0.2625960715 |
| GSE48662 | Down | -0.3830519963 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030702 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031100 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046167 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT048019 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
