HCSGD entry for STAT4

1. General information

Official gene symbolSTAT4
Entrez ID6775
Gene full namesignal transducer and activator of transcription 4
Other gene symbolsSLEB11
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006468Protein phosphorylationIEAbiological_process
GO:0007259JAK-STAT cascadeTASbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0019221Cytokine-mediated signaling pathwayIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01437204130.67463706550.29727496081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3424013094
GSE13712_SHEARDown-0.1452415380
GSE13712_STATICDown-0.4355623080
GSE19018Down-0.2633309626
GSE19899_A1Up0.2610019887
GSE19899_A2Up1.4457688211
PubMed_21979375_A1Up1.4534005264
PubMed_21979375_A2Up1.0958471823
GSE35957Up0.0252928072
GSE36640Up0.4149434241
GSE54402Up0.3588130424
GSE9593Up0.2782185048
GSE43922Up0.5649012049
GSE24585Up0.7807076475
GSE37065Up0.1425433806
GSE28863_A1Down-0.4311631118
GSE28863_A2Up0.1285436584
GSE28863_A3Down-0.0693729031
GSE28863_A4Down-0.0678212630
GSE48662Down-0.0580690309

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.