HCSGD entry for ST5
1. General information
| Official gene symbol | ST5 |
|---|---|
| Entrez ID | 6764 |
| Gene full name | suppression of tumorigenicity 5 |
| Other gene symbols | DENND2B HTS1 p126 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0361118992 | 0.3592429315 | 0.4316536331 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4767797605 |
| GSE13712_SHEAR | Down | -0.0914491527 |
| GSE13712_STATIC | Down | -0.3210442500 |
| GSE19018 | Down | -1.0995944150 |
| GSE19899_A1 | Up | 0.3638531686 |
| GSE19899_A2 | Up | 0.4546004616 |
| PubMed_21979375_A1 | Up | 1.0915631996 |
| PubMed_21979375_A2 | Up | 2.3676696098 |
| GSE35957 | Up | 0.2773112364 |
| GSE36640 | Down | -0.0782633454 |
| GSE54402 | Down | -0.0164980688 |
| GSE9593 | Up | 0.1986081552 |
| GSE43922 | Up | 0.2903840671 |
| GSE24585 | Up | 0.2304547029 |
| GSE37065 | Down | -0.4142803005 |
| GSE28863_A1 | Up | 0.6043879412 |
| GSE28863_A2 | Down | -0.0664461346 |
| GSE28863_A3 | Up | 0.1594337826 |
| GSE28863_A4 | Down | -0.0348628001 |
| GSE48662 | Up | 0.3560297388 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027459 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
