HCSGD entry for SSB
1. General information
| Official gene symbol | SSB |
|---|---|
| Entrez ID | 6741 |
| Gene full name | Sjogren syndrome antigen B (autoantigen La) |
| Other gene symbols | LARP3 La |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | TAS | molecular_function |
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003729 | MRNA binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006396 | RNA processing | IEA | biological_process |
| GO:0006400 | TRNA modification | TAS | biological_process |
| GO:0008334 | Histone mRNA metabolic process | TAS | biological_process |
| GO:0030529 | Ribonucleoprotein complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4508484860 | 0.6400207629 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1561020702 |
| GSE13712_SHEAR | Down | -0.0451796691 |
| GSE13712_STATIC | Down | -0.0304287921 |
| GSE19018 | Down | -0.2031584486 |
| GSE19899_A1 | Up | 0.5644305268 |
| GSE19899_A2 | Up | 0.2475225504 |
| PubMed_21979375_A1 | Up | 0.2074478508 |
| PubMed_21979375_A2 | Down | -0.1067014866 |
| GSE35957 | Down | -0.1505145418 |
| GSE36640 | Down | -0.0291264692 |
| GSE54402 | Up | 0.0885237773 |
| GSE9593 | Down | -0.0162448154 |
| GSE43922 | Up | 0.1438608261 |
| GSE24585 | Down | -0.3052015475 |
| GSE37065 | Down | -0.0926729827 |
| GSE28863_A1 | Down | -0.0118656240 |
| GSE28863_A2 | Up | 0.0283853668 |
| GSE28863_A3 | Up | 0.0268994704 |
| GSE28863_A4 | Down | -0.0306637726 |
| GSE48662 | Up | 0.0133781600 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038547 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051494 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25322305 | OBJECTIVES: We tested whether leukocyte telomere length maintenance, which underlies healthy cellular aging, provides a link between sugar-sweetened beverage (SSB) consumption and the risk of cardiometabolic disease |
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