HCSGD entry for SRPR
1. General information
| Official gene symbol | SRPR |
|---|---|
| Entrez ID | 6734 |
| Gene full name | signal recognition particle receptor (docking protein) |
| Other gene symbols | DP Sralpha |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005047 | Signal recognition particle binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005785 | Signal recognition particle receptor complex | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006613 | Cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0977673645 | 0.9094517306 | 0.6534623667 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3012356620 |
| GSE13712_SHEAR | Down | -0.0273919288 |
| GSE13712_STATIC | Up | 0.1871595836 |
| GSE19018 | Down | -0.1238621827 |
| GSE19899_A1 | Down | -0.0078874020 |
| GSE19899_A2 | Up | 0.4006025624 |
| PubMed_21979375_A1 | Up | 0.7092825781 |
| PubMed_21979375_A2 | Down | -0.0478083064 |
| GSE35957 | Up | 0.0746030900 |
| GSE36640 | Up | 0.7506016283 |
| GSE54402 | Up | 0.3042676340 |
| GSE9593 | Up | 0.3789797107 |
| GSE43922 | Up | 0.2514412124 |
| GSE24585 | Down | -0.0898118098 |
| GSE37065 | Down | -0.0816318522 |
| GSE28863_A1 | Up | 0.1497403450 |
| GSE28863_A2 | Up | 0.0390761350 |
| GSE28863_A3 | Down | -0.4188467020 |
| GSE28863_A4 | Up | 0.0097634083 |
| GSE48662 | Up | 0.0245132677 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001409 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023411 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-1-3p | MIMAT0004674 | MIRT038541 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039433 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042184 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042488 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049696 | CLASH//qRT-PCR | Functional MTI (WeaK) | 23622248 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT050050 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050241 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
