HCSGD entry for SRPK1
1. General information
| Official gene symbol | SRPK1 |
|---|---|
| Entrez ID | 6732 |
| Gene full name | SRSF protein kinase 1 |
| Other gene symbols | SFRSK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA IEA | molecular_function |
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0007059 | Chromosome segregation | IDA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016363 | Nuclear matrix | IEA | cellular_component |
| GO:0035092 | Sperm chromatin condensation | TAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0045070 | Positive regulation of viral genome replication | IDA | biological_process |
| GO:0045071 | Negative regulation of viral genome replication | IDA | biological_process |
| GO:0045087 | Innate immune response | IC | biological_process |
| GO:0048024 | Regulation of mRNA splicing, via spliceosome | TAS | biological_process |
| GO:0050684 | Regulation of mRNA processing | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0552202120 | 0.2103285248 | 0.5117883222 | 0.8859983677 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1990039723 |
| GSE13712_SHEAR | Up | 0.1629075968 |
| GSE13712_STATIC | Down | -0.0984236415 |
| GSE19018 | Down | -0.0285224649 |
| GSE19899_A1 | Up | 0.6880119949 |
| GSE19899_A2 | Up | 0.7915198169 |
| PubMed_21979375_A1 | Up | 0.8760321657 |
| PubMed_21979375_A2 | Up | 0.7619934183 |
| GSE35957 | Down | -0.0670873583 |
| GSE36640 | Down | -0.4768059477 |
| GSE54402 | Up | 1.0399647301 |
| GSE9593 | Down | -0.0315785096 |
| GSE43922 | Up | 0.2809933379 |
| GSE24585 | Down | -0.5582458205 |
| GSE37065 | Up | 0.1163437672 |
| GSE28863_A1 | Down | -0.5610857616 |
| GSE28863_A2 | Up | 0.1323575110 |
| GSE28863_A3 | Down | -0.8441168129 |
| GSE28863_A4 | Down | -0.1696580663 |
| GSE48662 | Down | -0.2585056490 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-5p | MIMAT0000093 | MIRT028016 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031711 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039559 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045199 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048634 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
