HCSGD entry for SPTBN2
1. General information
| Official gene symbol | SPTBN2 |
|---|---|
| Entrez ID | 6712 |
| Gene full name | spectrin, beta, non-erythrocytic 2 |
| Other gene symbols | GTRAP41 SCA5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005543 | Phospholipid binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007416 | Synapse assembly | IEA | biological_process |
| GO:0008091 | Spectrin | IDA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016192 | Vesicle-mediated transport | IDA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0021692 | Cerebellar Purkinje cell layer morphogenesis | IEA | biological_process |
| GO:0030534 | Adult behavior | IEA | biological_process |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0051693 | Actin filament capping | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6255585578 | 0.5327616770 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0511858071 |
| GSE13712_SHEAR | Up | 0.2321250442 |
| GSE13712_STATIC | Down | -0.2324980233 |
| GSE19018 | Down | -0.0169947428 |
| GSE19899_A1 | Down | -0.0830658652 |
| GSE19899_A2 | Down | -0.0337623866 |
| PubMed_21979375_A1 | Up | 0.1289565347 |
| PubMed_21979375_A2 | Down | -0.0510100711 |
| GSE35957 | Down | -0.1407253921 |
| GSE36640 | Up | 0.0515388567 |
| GSE54402 | Up | 0.0230908515 |
| GSE9593 | Down | -0.1005315967 |
| GSE43922 | Up | 0.0520545586 |
| GSE24585 | Down | -0.5777858424 |
| GSE37065 | Up | 0.0505687128 |
| GSE28863_A1 | Down | -0.0171527903 |
| GSE28863_A2 | Up | 0.0127958799 |
| GSE28863_A3 | Up | 0.2864070785 |
| GSE28863_A4 | Up | 0.1624732767 |
| GSE48662 | Up | 0.1275072830 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018419 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031841 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-330-5p | MIMAT0004693 | MIRT038253 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041544 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046696 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052103 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
