HCSGD entry for SPINK2
1. General information
| Official gene symbol | SPINK2 |
|---|---|
| Entrez ID | 6691 |
| Gene full name | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| Other gene symbols | HUSI-II |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001669 | Acrosomal vesicle | IEA | cellular_component |
| GO:0002176 | Male germ cell proliferation | IEA | biological_process |
| GO:0004866 | Endopeptidase inhibitor activity | TAS | molecular_function |
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0007286 | Spermatid development | IEA | biological_process |
| GO:0009566 | Fertilization | IEA | biological_process |
| GO:0072520 | Seminiferous tubule development | IEA | biological_process |
| GO:1900004 | Negative regulation of serine-type endopeptidase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4321665020 | 0.8851148703 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1099710883 |
| GSE13712_SHEAR | Up | 0.0632318972 |
| GSE13712_STATIC | Down | -0.0862159089 |
| GSE19018 | Down | -0.0953779488 |
| GSE19899_A1 | Up | 0.2342568982 |
| GSE19899_A2 | Up | 0.0962719939 |
| PubMed_21979375_A1 | Down | -0.0246608170 |
| PubMed_21979375_A2 | Down | -0.0381695482 |
| GSE35957 | Up | 0.1222608561 |
| GSE36640 | Up | 0.1287854465 |
| GSE54402 | Down | -0.0638105167 |
| GSE9593 | Down | -0.1237412986 |
| GSE43922 | Up | 0.0173583427 |
| GSE24585 | Up | 0.7986808004 |
| GSE37065 | Up | 0.0048005289 |
| GSE28863_A1 | Up | 0.0054317028 |
| GSE28863_A2 | Down | -0.1298575922 |
| GSE28863_A3 | Up | 0.0913952261 |
| GSE28863_A4 | Down | -0.0168362426 |
| GSE48662 | Up | 0.0362720014 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
