HCSGD entry for SPIB
1. General information
| Official gene symbol | SPIB |
|---|---|
| Entrez ID | 6689 |
| Gene full name | Spi-B transcription factor (Spi-1/PU.1 related) |
| Other gene symbols | SPI-B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003887 | DNA-directed DNA polymerase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6299593025 | 0.6897151248 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0041363105 |
| GSE13712_SHEAR | Down | -0.0631520056 |
| GSE13712_STATIC | Down | -0.0378082690 |
| GSE19018 | Down | -0.0420081668 |
| GSE19899_A1 | Up | 0.0496063603 |
| GSE19899_A2 | Up | 0.1259849257 |
| PubMed_21979375_A1 | Up | 0.0708252667 |
| PubMed_21979375_A2 | Down | -0.0181857541 |
| GSE35957 | Up | 0.0289640293 |
| GSE36640 | Up | 0.0863247840 |
| GSE54402 | Up | 0.0218501506 |
| GSE9593 | Up | 0.1010872394 |
| GSE43922 | Up | 0.1294570469 |
| GSE24585 | Down | -0.1021778563 |
| GSE37065 | Down | -0.1156426264 |
| GSE28863_A1 | Down | -0.4667170688 |
| GSE28863_A2 | Down | -0.1813361772 |
| GSE28863_A3 | Up | 0.4837442030 |
| GSE28863_A4 | Up | 0.1390605051 |
| GSE48662 | Up | 0.0712357093 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
