HCSGD entry for SPAM1
1. General information
| Official gene symbol | SPAM1 |
|---|---|
| Entrez ID | 6677 |
| Gene full name | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| Other gene symbols | HYA1 HYAL1 HYAL3 HYAL5 PH-20 PH20 SPAG15 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004415 | Hyalurononglucosaminidase activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007338 | Single fertilization | TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | TAS | biological_process |
| GO:0007342 | Fusion of sperm to egg plasma membrane | IEA | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0032504 | Multicellular organism reproduction | TAS | biological_process |
| GO:0035036 | Sperm-egg recognition | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7863471411 | 0.8382802021 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0203975319 |
| GSE13712_SHEAR | Down | -0.1106540338 |
| GSE13712_STATIC | Down | -0.0494128184 |
| GSE19018 | Up | 0.0709339134 |
| GSE19899_A1 | Up | 0.1768626831 |
| GSE19899_A2 | Up | 0.1091952276 |
| PubMed_21979375_A1 | Up | 0.0318326040 |
| PubMed_21979375_A2 | Down | -0.0822944848 |
| GSE35957 | Up | 0.1829093532 |
| GSE36640 | Up | 0.0683494800 |
| GSE54402 | Up | 0.0325566457 |
| GSE9593 | Up | 0.0827089478 |
| GSE43922 | Up | 0.0156621620 |
| GSE24585 | Down | -0.1741987970 |
| GSE37065 | Down | -0.0489204804 |
| GSE28863_A1 | Down | -0.1000862248 |
| GSE28863_A2 | Down | -0.0843117912 |
| GSE28863_A3 | Up | 0.1335131277 |
| GSE28863_A4 | Up | 0.0043510148 |
| GSE48662 | Up | 0.1438563037 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
