HCSGD entry for SP4
1. General information
| Official gene symbol | SP4 |
|---|---|
| Entrez ID | 6671 |
| Gene full name | Sp4 transcription factor |
| Other gene symbols | HF1B SPR-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0008016 | Regulation of heart contraction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9726027089 | 0.0329068994 | 0.9999902473 | 0.3423220861 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2261584819 |
| GSE13712_SHEAR | Down | -0.3220679440 |
| GSE13712_STATIC | Down | -0.2065315340 |
| GSE19018 | Up | 0.1054501343 |
| GSE19899_A1 | Down | -0.0915401143 |
| GSE19899_A2 | Down | -0.6320091400 |
| PubMed_21979375_A1 | Down | -0.1469055586 |
| PubMed_21979375_A2 | Down | -0.7701945408 |
| GSE35957 | Down | -0.1272225689 |
| GSE36640 | Down | -1.4236207991 |
| GSE54402 | Up | 0.1045836446 |
| GSE9593 | Down | -0.3314369470 |
| GSE43922 | Down | -0.2672275454 |
| GSE24585 | Up | 0.2932296247 |
| GSE37065 | Down | -0.0013848567 |
| GSE28863_A1 | Up | 0.2776078107 |
| GSE28863_A2 | Up | 0.1239743194 |
| GSE28863_A3 | Down | -0.2860917354 |
| GSE28863_A4 | Down | -0.2374702851 |
| GSE48662 | Down | -0.1653765568 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-27a-3p | MIMAT0000084 | MIRT002401 | Western blot | Functional MTI | 18006846 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT002401 | Western blot;qRT-PCR | Functional MTI | 20382698 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018082 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026542 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029593 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
