HCSGD entry for SORL1

1. General information

Official gene symbolSORL1
Entrez ID6653
Gene full namesortilin-related receptor, L(DLR class) A repeats containing
Other gene symbolsC11orf32 LR11 LRP9 SORLA SorLA-1 gp250
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0005768EndosomeIDAcellular_component
GO:0005771Multivesicular bodyIEAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006605Protein targetingIMPbiological_process
GO:0006869Lipid transportIEAbiological_process
GO:0006898Receptor-mediated endocytosisTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008203Cholesterol metabolic processIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0014910Regulation of smooth muscle cell migrationIDAbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016477Cell migrationIEAbiological_process
GO:0030169Low-density lipoprotein particle bindingIPImolecular_function
GO:0034362Low-density lipoprotein particleIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98517412330.01980790620.99999024730.2736818373

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1222303303
GSE13712_SHEARDown-0.1583114572
GSE13712_STATICDown-0.0863612154
GSE19018Down-0.2381822853
GSE19899_A1Down-0.0715388786
GSE19899_A2Down-1.0711515555
PubMed_21979375_A1Down-1.3317257821
PubMed_21979375_A2Down-0.4399809515
GSE35957Up0.0676049317
GSE36640Up0.0582554510
GSE54402Down-1.4064073605
GSE9593Up0.1126066243
GSE43922Down-1.4011930207
GSE24585Down-0.0976636377
GSE37065Down-0.0195039909
GSE28863_A1Down-0.2260118005
GSE28863_A2Down-0.2798717337
GSE28863_A3Up0.1387159188
GSE28863_A4Up0.0429828283
GSE48662Down-0.0324758297

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.