HCSGD entry for SON
1. General information
| Official gene symbol | SON |
|---|---|
| Entrez ID | 6651 |
| Gene full name | SON DNA binding protein |
| Other gene symbols | BASS1 C21orf50 DBP-5 NREBP SON3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IMP | biological_process |
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0003676 | Nucleic acid binding | IEA TAS | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006397 | MRNA processing | IDA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
| GO:0043484 | Regulation of RNA splicing | IDA | biological_process |
| GO:0050733 | RS domain binding | IEA | molecular_function |
| GO:0051726 | Regulation of cell cycle | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2731611299 | 0.7969940580 | 0.9702070937 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1308780785 |
| GSE13712_SHEAR | Up | 0.0435445446 |
| GSE13712_STATIC | Down | -0.0106554098 |
| GSE19018 | Down | -0.1300847549 |
| GSE19899_A1 | Up | 0.2555528022 |
| GSE19899_A2 | Up | 0.0507082585 |
| PubMed_21979375_A1 | Up | 0.1834751480 |
| PubMed_21979375_A2 | Up | 0.4949264948 |
| GSE35957 | Up | 0.1387761144 |
| GSE36640 | Down | -0.2629284058 |
| GSE54402 | Down | -0.0254163568 |
| GSE9593 | Down | -0.1236456401 |
| GSE43922 | Down | -0.0328082906 |
| GSE24585 | Up | 0.1104339970 |
| GSE37065 | Up | 0.0333764616 |
| GSE28863_A1 | Up | 0.7499384893 |
| GSE28863_A2 | Up | 0.5666112860 |
| GSE28863_A3 | Down | -0.1743586505 |
| GSE28863_A4 | Up | 0.0058352055 |
| GSE48662 | Up | 0.0992539215 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016074 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020220 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027080 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028488 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031190 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT031319 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031734 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031734 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035999 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036714 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037810 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT043008 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044070 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046623 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT047384 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050929 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052097 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
