HCSGD entry for SNX1
1. General information
| Official gene symbol | SNX1 |
|---|---|
| Entrez ID | 6642 |
| Gene full name | sorting nexin 1 |
| Other gene symbols | HsT17379 VPS5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005768 | Endosome | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA IMP | biological_process |
| GO:0006897 | Endocytosis | TAS | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0010008 | Endosome membrane | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016197 | Endosomal transport | IEA | biological_process |
| GO:0031901 | Early endosome membrane | IDA | cellular_component |
| GO:0034498 | Early endosome to Golgi transport | IMP | biological_process |
| GO:0035091 | Phosphatidylinositol binding | IDA IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045732 | Positive regulation of protein catabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1793094335 | 0.9001799362 | 0.8298933708 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1536600235 |
| GSE13712_SHEAR | Down | -0.1503963443 |
| GSE13712_STATIC | Down | -0.0070826508 |
| GSE19018 | Up | 0.0678638981 |
| GSE19899_A1 | Down | -0.1121969383 |
| GSE19899_A2 | Down | -0.2680469820 |
| PubMed_21979375_A1 | Down | -0.1712285279 |
| PubMed_21979375_A2 | Up | 0.2822801888 |
| GSE35957 | Up | 0.1585907971 |
| GSE36640 | Up | 0.3651911662 |
| GSE54402 | Down | -0.2577181102 |
| GSE9593 | Up | 0.4017024922 |
| GSE43922 | Up | 0.0568821482 |
| GSE24585 | Up | 0.2919240492 |
| GSE37065 | Down | -0.0033892397 |
| GSE28863_A1 | Up | 0.3742500623 |
| GSE28863_A2 | Up | 0.3905897202 |
| GSE28863_A3 | Down | -0.2715787777 |
| GSE28863_A4 | Up | 0.0385333451 |
| GSE48662 | Up | 0.5673627330 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-95-3p | MIMAT0000094 | MIRT006354 | Luciferase reporter assay//Western blot//Reporter assay | Functional MTI | 21427358 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT004201 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-28-3p | MIMAT0004502 | MIRT038943 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-28-5p | MIMAT0000085 | MIRT049992 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
