HCSGD entry for SNTA1

1. General information

Official gene symbolSNTA1
Entrez ID6640
Gene full namesyntrophin, alpha 1
Other gene symbolsLQT12 SNT1 TACIP1 dJ1187J4.5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002027Regulation of heart rateIMPbiological_process
GO:0003117Regulation of vasoconstriction by circulating norepinephrineIEAbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0016013Syntrophin complexTAScellular_component
GO:0016328Lateral plasma membraneTAScellular_component
GO:0017080Sodium channel regulator activityIMPmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030165PDZ domain bindingIEAmolecular_function
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0042383SarcolemmaIEAcellular_component
GO:0043234Protein complexIDAcellular_component
GO:0044325Ion channel bindingIPImolecular_function
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0050998Nitric-oxide synthase bindingIPImolecular_function
GO:0051117ATPase bindingIPImolecular_function
GO:0060307Regulation of ventricular cardiac muscle cell membrane repolarizationIMPbiological_process
GO:0086005Ventricular cardiac muscle cell action potentialIMPbiological_process
GO:1902083Negative regulation of peptidyl-cysteine S-nitrosylationIMPbiological_process
GO:1902305Regulation of sodium ion transmembrane transportIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73863654500.05297335210.99999024730.4340945205

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3719676597
GSE13712_SHEARDown-0.2898773292
GSE13712_STATICUp0.0768423397
GSE19018Up0.6716198642
GSE19899_A1Down-0.5198916913
GSE19899_A2Down-0.2299619426
PubMed_21979375_A1Down-0.2423435466
PubMed_21979375_A2Down-0.4846125773
GSE35957Up0.3206251273
GSE36640Up0.0481132470
GSE54402Down-0.1711080502
GSE9593Up0.7028002881
GSE43922Down-0.0923170923
GSE24585Up0.0383182277
GSE37065Down-0.0495166985
GSE28863_A1Down-0.3184823815
GSE28863_A2Down-0.2384398928
GSE28863_A3Down-0.5922047658
GSE28863_A4Down-0.0459642281
GSE48662Up0.3074089868

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022575MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.