HCSGD entry for BNIP2

1. General information

Official gene symbolBNIP2
Entrez ID663
Gene full nameBCL2/adenovirus E1B 19kDa interacting protein 2
Other gene symbolsBNIP-2 NIP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001824Blastocyst developmentIEAbiological_process
GO:0005096GTPase activator activityTASmolecular_function
GO:0005509Calcium ion bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005635Nuclear envelopeIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005814CentrioleIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006915Apoptotic processIPIbiological_process
GO:0031616Spindle pole centrosomeIEAcellular_component
GO:0042692Muscle cell differentiationTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0043085Positive regulation of catalytic activityTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0043410Positive regulation of MAPK cascadeIEAbiological_process
GO:0043547Positive regulation of GTPase activityTASbiological_process
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0051057Positive regulation of small GTPase mediated signal transductionIEAbiological_process
GO:0051146Striated muscle cell differentiationIEAbiological_process
GO:0051149Positive regulation of muscle cell differentiationTASbiological_process
GO:0051297Centrosome organizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07679462410.91785239540.58579991311.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0888452710
GSE13712_SHEARDown-0.0738731077
GSE13712_STATICDown-0.3294241613
GSE19018Up0.0351393589
GSE19899_A1Up0.2271801278
GSE19899_A2Up0.1298141031
PubMed_21979375_A1Down-0.0971372486
PubMed_21979375_A2Up0.4965031140
GSE35957Up0.4786032690
GSE36640Up0.5011646126
GSE54402Up0.0821795717
GSE9593Up0.4161016815
GSE43922Down-0.0504234844
GSE24585Up0.1497048458
GSE37065Up0.0919309573
GSE28863_A1Up0.3927365249
GSE28863_A2Up0.4905746349
GSE28863_A3Down-0.4638903020
GSE28863_A4Up0.2306787339
GSE48662Down-0.0357444842

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-20a-5pMIMAT0000075MIRT005481qRT-PCR//Western blotFunctional MTI21242194
hsa-miR-20a-5pMIMAT0000075MIRT005481CLASHFunctional MTI (Weak)23622248
hsa-miR-130b-3pMIMAT0000691MIRT020114SequencingFunctional MTI (Weak)20371350
hsa-miR-132-3pMIMAT0000426MIRT021762MicroarrayFunctional MTI (Weak)17612493
hsa-miR-93-5pMIMAT0000093MIRT027996SequencingFunctional MTI (Weak)20371350
hsa-miR-877-3pMIMAT0004950MIRT037172CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.