HCSGD entry for SNRNP70
1. General information
| Official gene symbol | SNRNP70 |
|---|---|
| Entrez ID | 6625 |
| Gene full name | small nuclear ribonucleoprotein 70kDa (U1) |
| Other gene symbols | RNPU1Z RPU1 SNRP70 Snp1 U1-70K U170K U1AP U1RNP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | IC IDA TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005685 | U1 snRNP | IDA | cellular_component |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0043484 | Regulation of RNA splicing | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5042531857 | 0.6248916417 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0159632534 |
| GSE13712_SHEAR | Down | -0.0220705000 |
| GSE13712_STATIC | Down | -0.0269160596 |
| GSE19018 | Up | 0.0046229257 |
| GSE19899_A1 | Down | -0.0973899214 |
| GSE19899_A2 | Up | 0.3128942811 |
| PubMed_21979375_A1 | Down | -0.4291268373 |
| PubMed_21979375_A2 | Down | -0.0584206233 |
| GSE35957 | Down | -0.2619740504 |
| GSE36640 | Up | 0.1513692676 |
| GSE54402 | Up | 0.0748272173 |
| GSE9593 | Down | -0.3602540261 |
| GSE43922 | Up | 0.2888513923 |
| GSE24585 | Down | -0.1093100159 |
| GSE37065 | Down | -0.0899865282 |
| GSE28863_A1 | Up | 0.0655752697 |
| GSE28863_A2 | Down | -0.0199932208 |
| GSE28863_A3 | Up | 0.4862812044 |
| GSE28863_A4 | Down | -0.0295577383 |
| GSE48662 | Up | 0.2831763147 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028809 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039874 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040687 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041276 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043521 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049622 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
