HCSGD entry for SNCB

1. General information

Official gene symbolSNCB
Entrez ID6620
Gene full namesynuclein, beta
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004859Phospholipase inhibitor activityTASmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0007268Synaptic transmissionIEAbiological_process
GO:0030426Growth coneIEAcellular_component
GO:0042417Dopamine metabolic processIEAbiological_process
GO:0043014Alpha-tubulin bindingIEAmolecular_function
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043086Negative regulation of catalytic activityTASbiological_process
GO:0043195Terminal boutonIEAcellular_component
GO:0043524Negative regulation of neuron apoptotic processIEAbiological_process
GO:0048487Beta-tubulin bindingIEAmolecular_function
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0050808Synapse organizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01220717300.97724948140.27579828331.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0809188748
GSE13712_SHEARUp0.1269983751
GSE13712_STATICDown-0.0851621869
GSE19018Up0.0081291033
GSE19899_A1Up0.3763796717
GSE19899_A2Up1.0588398497
PubMed_21979375_A1Up0.5936972227
PubMed_21979375_A2Up1.5393073230
GSE35957Up0.0507009954
GSE36640Up0.1194099202
GSE54402Up1.3520843286
GSE9593Up0.2012956159
GSE43922Up0.7718905759
GSE24585Down-0.2682461257
GSE37065Down-0.0886934528
GSE28863_A1Down-0.0884841903
GSE28863_A2Up0.0946870687
GSE28863_A3Up0.2784855221
GSE28863_A4Up0.0382760314
GSE48662Up0.9899395142

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018267MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.