HCSGD entry for SNAP25

1. General information

Official gene symbolSNAP25
Entrez ID6616
Gene full namesynaptosomal-associated protein, 25kDa
Other gene symbolsRIC-4 RIC4 SEC9 SNAP SNAP-25 bA416N4.2 dJ1068F16.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000149SNARE bindingIEAmolecular_function
GO:0001504Neurotransmitter uptakeNASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005802Trans-Golgi networkIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007268Synaptic transmissionNAS TASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0014047Glutamate secretionTASbiological_process
GO:0016020MembraneISScellular_component
GO:0016081Synaptic vesicle docking involved in exocytosisNASbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030426Growth coneISScellular_component
GO:0031083BLOC-1 complexIDAcellular_component
GO:0031201SNARE complexIDA ISScellular_component
GO:0043005Neuron projectionISScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045202SynapseIEAcellular_component
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050796Regulation of insulin secretionTASbiological_process
GO:0070032Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98582658330.01113471750.99999024730.2084632290

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0219800244
GSE13712_SHEARDown-0.0509811418
GSE13712_STATICDown-0.2072308031
GSE19018Down-0.3463280648
GSE19899_A1Down-0.3033608527
GSE19899_A2Down-0.8736086543
PubMed_21979375_A1Down-0.2769992233
PubMed_21979375_A2Down-1.0132356930
GSE35957Down-0.6329331201
GSE36640Down-0.4199477550
GSE54402Down-0.7643403655
GSE9593Down-0.8026678748
GSE43922Down-0.5570883882
GSE24585Down-0.1656529260
GSE37065Down-0.1796880481
GSE28863_A1Up0.0084435290
GSE28863_A2Up0.2470094867
GSE28863_A3Up0.1392173718
GSE28863_A4Down-0.0906103762
GSE48662Down-0.0162428524

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Botulinum Toxin Type ADB00083 BTD00092 | BIOD00092

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.