HCSGD entry for POLR3D

1. General information

Official gene symbolPOLR3D
Entrez ID661
Gene full namepolymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Other gene symbolsBN51T RPC4 RPC53 TSBN51
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005666DNA-directed RNA polymerase III complexIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006383Transcription from RNA polymerase III promoterIEA TASbiological_process
GO:0006385Transcription elongation from RNA polymerase III promoterTASbiological_process
GO:0006386Termination of RNA polymerase III transcriptionTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0032728Positive regulation of interferon-beta productionIDAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045089Positive regulation of innate immune responseIDAbiological_process
GO:0051607Defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11440445270.35947098130.69527582541.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0740510191
GSE13712_SHEARUp0.1040761458
GSE13712_STATICDown-0.0818085239
GSE19018Down-0.6381952648
GSE19899_A1Up0.1701500967
GSE19899_A2Up0.6835014894
PubMed_21979375_A1Up1.0422654046
PubMed_21979375_A2Up0.9407872114
GSE35957Down-0.4955230537
GSE36640Up0.1911954636
GSE54402Up0.2776689454
GSE9593Down-0.6584718297
GSE43922Up0.4491401290
GSE24585Down-0.4796601211
GSE37065Down-0.2676195948
GSE28863_A1Up0.1248000813
GSE28863_A2Up0.3544635304
GSE28863_A3Down-0.0188835450
GSE28863_A4Down-0.1281635704
GSE48662Up0.0655910649

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-149-5pMIMAT0000450MIRT045444CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051623CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.