HCSGD entry for HLTF
1. General information
| Official gene symbol | HLTF |
|---|---|
| Entrez ID | 6596 |
| Gene full name | helicase-like transcription factor |
| Other gene symbols | HIP116 HIP116A HLTF1 RNF80 SMARCA3 SNF2L3 ZBU1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0016887 | ATPase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9718879298 | 0.0004433494 | 0.9999902473 | 0.0389893333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3681331609 |
| GSE13712_SHEAR | Down | -1.2687742225 |
| GSE13712_STATIC | Down | -0.7284115754 |
| GSE19018 | Up | 0.8988391116 |
| GSE19899_A1 | Down | -0.8661386704 |
| GSE19899_A2 | Down | -2.4620763372 |
| PubMed_21979375_A1 | Down | -2.3853678902 |
| PubMed_21979375_A2 | Down | -2.4697086345 |
| GSE35957 | Down | -1.0065849280 |
| GSE36640 | Down | -0.2807670248 |
| GSE54402 | Down | -0.5590190474 |
| GSE9593 | Down | -0.3053387365 |
| GSE43922 | Down | -1.2830274794 |
| GSE24585 | Up | 0.3113542925 |
| GSE37065 | Down | -0.1592864170 |
| GSE28863_A1 | Down | -0.2242493278 |
| GSE28863_A2 | Up | 0.6577870835 |
| GSE28863_A3 | Down | -0.5887080646 |
| GSE28863_A4 | Down | -0.2290721020 |
| GSE48662 | Down | -0.7297304531 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT021505 | Reporter assay;Microarray | Functional MTI | 21351259 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
