HCSGD entry for SLN

1. General information

Official gene symbolSLN
Entrez ID6588
Gene full namesarcolipin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004857Enzyme inhibitor activityISSmolecular_function
GO:0006816Calcium ion transportNASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0016529Sarcoplasmic reticulumIDAcellular_component
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0043086Negative regulation of catalytic activityISSbiological_process
GO:0043242Negative regulation of protein complex disassemblyISSbiological_process
GO:0051117ATPase bindingISSmolecular_function
GO:0051924Regulation of calcium ion transportISSbiological_process
GO:0070296Sarcoplasmic reticulum calcium ion transportISSbiological_process
GO:0090281Negative regulation of calcium ion importISSbiological_process
GO:1901020Negative regulation of calcium ion transmembrane transporter activityISSbiological_process
GO:1901077Regulation of relaxation of muscleISSbiological_process
GO:1901877Negative regulation of calcium ion bindingISSbiological_process
GO:1901881Positive regulation of protein depolymerizationISSbiological_process
GO:1901894Regulation of calcium-transporting ATPase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44738606060.86427915350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1033593617
GSE13712_SHEARUp0.0087312434
GSE13712_STATICUp0.2151729774
GSE19018Up0.0963581378
GSE19899_A1Up0.2167185543
GSE19899_A2Up0.0312529467
PubMed_21979375_A1Up0.0083524224
PubMed_21979375_A2Up0.2341786141
GSE35957Up0.1401132623
GSE36640Up0.2926880357
GSE54402Up0.0629947324
GSE9593Down-0.0686376914
GSE43922Up0.0119455492
GSE24585Down-0.1971921269
GSE37065Up0.2760326544
GSE28863_A1Down-0.0099391133
GSE28863_A2Up0.0131007019
GSE28863_A3Down-0.1228280192
GSE28863_A4Down-0.1524858744
GSE48662Down-0.0624503875

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.