HCSGD entry for SLC22A2


1. General information

Official gene symbolSLC22A2
Entrez ID6582
Gene full namesolute carrier family 22 (organic cation transporter), member 2
Other gene symbolsOCT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005496Steroid bindingIEAmolecular_function
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006855Drug transmembrane transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0007589Body fluid secretionTASbiological_process
GO:0015101Organic cation transmembrane transporter activityIDAmolecular_function
GO:0015220Choline transmembrane transporter activityIEAmolecular_function
GO:0015651Quaternary ammonium group transmembrane transporter activityIEAmolecular_function
GO:0015695Organic cation transportIDAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0042136Neurotransmitter biosynthetic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051608Histamine transportIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56017652060.89812894650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0783872913
GSE13712_SHEARUp0.1985122372
GSE13712_STATICUp0.0059774776
GSE19018Up0.0471101510
GSE19899_A1Up0.0891192890
GSE19899_A2Up0.1663129763
PubMed_21979375_A1Down-0.0959241734
PubMed_21979375_A2Up0.0520022515
GSE35957Up0.0907076749
GSE36640Up0.1943848506
GSE54402Up0.1135282976
GSE9593Down-0.0336471820
GSE43922Up0.0147879319
GSE24585Up0.0593407036
GSE37065Down-0.0321943753
GSE28863_A1Down-0.0919302211
GSE28863_A2Down-0.0388023723
GSE28863_A3Up0.0628646164
GSE28863_A4Down-0.0195130295
GSE48662Up0.5003079720

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017635MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.