HCSGD entry for SLC19A1
1. General information
| Official gene symbol | SLC19A1 |
|---|---|
| Entrez ID | 6573 |
| Gene full name | solute carrier family 19 (folate transporter), member 1 |
| Other gene symbols | CHMD FOLT IFC1 REFC RFC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005542 | Folic acid binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0008517 | Folic acid transporter activity | IEA | molecular_function |
| GO:0015350 | Methotrexate transporter activity | IEA | molecular_function |
| GO:0015884 | Folic acid transport | TAS | biological_process |
| GO:0016020 | Membrane | IEA TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046655 | Folic acid metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9195114699 | 0.1175089700 | 0.9999902473 | 0.6577509037 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1246477569 |
| GSE13712_SHEAR | Up | 0.1351921512 |
| GSE13712_STATIC | Up | 0.1872769108 |
| GSE19018 | Up | 0.0239266141 |
| GSE19899_A1 | Up | 0.0248983649 |
| GSE19899_A2 | Down | -0.0795202749 |
| PubMed_21979375_A1 | Down | -0.4121959618 |
| PubMed_21979375_A2 | Down | -0.2145434511 |
| GSE35957 | Down | -0.1351467162 |
| GSE36640 | Down | -0.3942970146 |
| GSE54402 | Down | -0.0689255088 |
| GSE9593 | Down | -0.2522787745 |
| GSE43922 | Up | 0.0542400020 |
| GSE24585 | Down | -0.9107100163 |
| GSE37065 | Down | -0.4519420960 |
| GSE28863_A1 | Down | -0.0238040735 |
| GSE28863_A2 | Up | 0.1148483881 |
| GSE28863_A3 | Up | 0.2168087116 |
| GSE28863_A4 | Up | 0.1564652004 |
| GSE48662 | Up | 0.0293085775 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042257 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045982 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048799 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051284 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
