HCSGD entry for SLC9A2
1. General information
| Official gene symbol | SLC9A2 |
|---|---|
| Entrez ID | 6549 |
| Gene full name | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| Other gene symbols | NHE2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006885 | Regulation of pH | IEA | biological_process |
| GO:0008104 | Protein localization | IEA | biological_process |
| GO:0015385 | Sodium:hydrogen antiporter activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902600 | Hydrogen ion transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9254499791 | 0.5529748148 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1057134013 |
| GSE13712_SHEAR | Up | 0.0865412323 |
| GSE13712_STATIC | Up | 0.0342730255 |
| GSE19018 | Down | -0.0447198378 |
| GSE19899_A1 | Down | -0.1995491932 |
| GSE19899_A2 | Up | 0.0239155896 |
| PubMed_21979375_A1 | Up | 0.0261104467 |
| PubMed_21979375_A2 | Down | -0.2316636919 |
| GSE35957 | Up | 0.0559601181 |
| GSE36640 | Down | -0.0546600450 |
| GSE54402 | Up | 0.0846096324 |
| GSE9593 | Up | 0.0697088162 |
| GSE43922 | Up | 0.0162784749 |
| GSE24585 | Down | -0.2057366327 |
| GSE37065 | Down | -0.0991541931 |
| GSE28863_A1 | Down | -0.0834218125 |
| GSE28863_A2 | Up | 0.0730830137 |
| GSE28863_A3 | Up | 0.1079005608 |
| GSE28863_A4 | Up | 0.1181780294 |
| GSE48662 | Up | 0.0101931403 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT051193 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 18845559 | Two of these, SLC26a3/DRA (downregulated in adenoma) and Na+/H+ exchanger 2 (NHE2), were not previously known to be elevated in BE; however, we confirmed their elevation in BE tissue samples |
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