HCSGD entry for SLC8A3


1. General information

Official gene symbolSLC8A3
Entrez ID6547
Gene full namesolute carrier family 8 (sodium/calcium exchanger), member 3
Other gene symbolsNCX3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005432Calcium:sodium antiporter activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006811Ion transportTASbiological_process
GO:0007154Cell communicationIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0021537Telencephalon developmentIEAbiological_process
GO:0042383SarcolemmaIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043197Dendritic spineIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
GO:0060402Calcium ion transport into cytosolIEAbiological_process
GO:0071320Cellular response to cAMPIEAbiological_process
GO:1990034Calcium ion export from cellIEAbiological_process
GO:1990035Calcium ion import into cellIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20841135220.94853108540.88023686071.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0006962740
GSE13712_SHEARUp0.0470838882
GSE13712_STATICUp0.1233610659
GSE19018Up0.2169869792
GSE19899_A1Up0.0888547974
GSE19899_A2Down-0.0954843088
PubMed_21979375_A1Up0.0694343691
PubMed_21979375_A2Up0.0355974440
GSE35957Up0.3446626577
GSE36640Up1.0833324102
GSE54402Up0.7558799696
GSE9593Down-0.0142613046
GSE43922Up0.0147776197
GSE24585Down-0.0103463394
GSE37065Down-0.0121417287
GSE28863_A1Down-0.0500248445
GSE28863_A2Down-0.0670456837
GSE28863_A3Up0.1230979799
GSE28863_A4Down-0.0125678611
GSE48662Up0.0872281274

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.