HCSGD entry for SLC7A2
1. General information
| Official gene symbol | SLC7A2 |
|---|---|
| Entrez ID | 6542 |
| Gene full name | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| Other gene symbols | ATRC2 CAT2 HCAT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000064 | L-ornithine transmembrane transporter activity | IEA | molecular_function |
| GO:0002537 | Nitric oxide production involved in inflammatory response | IEA | biological_process |
| GO:0005289 | High affinity arginine transmembrane transporter activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0006809 | Nitric oxide biosynthetic process | IEA | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006865 | Amino acid transport | TAS | biological_process |
| GO:0015174 | Basic amino acid transmembrane transporter activity | TAS | molecular_function |
| GO:0015189 | L-lysine transmembrane transporter activity | IEA | molecular_function |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0042116 | Macrophage activation | IEA | biological_process |
| GO:0043030 | Regulation of macrophage activation | IEA | biological_process |
| GO:0050727 | Regulation of inflammatory response | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9274550131 | 0.0176656700 | 0.9999902473 | 0.2605587115 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0943621073 |
| GSE13712_SHEAR | Up | 0.0415143581 |
| GSE13712_STATIC | Up | 0.1767478875 |
| GSE19018 | Down | -0.2418922077 |
| GSE19899_A1 | Down | -0.0450253281 |
| GSE19899_A2 | Down | -0.1956527495 |
| PubMed_21979375_A1 | Down | -0.4908273215 |
| PubMed_21979375_A2 | Down | -0.9236604743 |
| GSE35957 | Down | -0.2171479135 |
| GSE36640 | Down | -0.7675125192 |
| GSE54402 | Down | -0.3570641426 |
| GSE9593 | Down | -0.4474080185 |
| GSE43922 | Down | -0.7056503443 |
| GSE24585 | Down | -0.7340654252 |
| GSE37065 | Up | 0.9733973373 |
| GSE28863_A1 | Down | -0.0197674349 |
| GSE28863_A2 | Up | 0.0425336394 |
| GSE28863_A3 | Up | 0.1974446529 |
| GSE28863_A4 | Down | -0.0952356392 |
| GSE48662 | Down | -0.1183710659 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021331 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026256 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027260 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030407 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038121 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-2-3p | MIMAT0004550 | MIRT038694 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040049 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
