HCSGD entry for SLC6A11
1. General information
| Official gene symbol | SLC6A11 |
|---|---|
| Entrez ID | 6538 |
| Gene full name | solute carrier family 6 (neurotransmitter transporter, GABA), member 11 |
| Other gene symbols | GAT-3 GAT3 GAT4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005328 | Neurotransmitter:sodium symporter activity | IEA | molecular_function |
| GO:0005332 | Gamma-aminobutyric acid:sodium symporter activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007269 | Neurotransmitter secretion | TAS | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA TAS | cellular_component |
| GO:0042165 | Neurotransmitter binding | IEA | molecular_function |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8479386156 | 0.7865565404 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0514950776 |
| GSE13712_SHEAR | Down | -0.0734645344 |
| GSE13712_STATIC | Up | 0.0046978448 |
| GSE19018 | Up | 0.0710109995 |
| GSE19899_A1 | Down | -0.0596547436 |
| GSE19899_A2 | Up | 0.2734058976 |
| PubMed_21979375_A1 | Up | 0.0787662081 |
| PubMed_21979375_A2 | Down | -0.0883264980 |
| GSE35957 | Up | 0.0702531849 |
| GSE36640 | Down | -0.0273616190 |
| GSE54402 | Up | 0.0391982890 |
| GSE9593 | Up | 0.0554357642 |
| GSE43922 | Up | 0.0244253065 |
| GSE24585 | Down | -0.1830760388 |
| GSE37065 | Down | -0.0725441905 |
| GSE28863_A1 | Down | -0.1174783209 |
| GSE28863_A2 | Up | 0.0565244709 |
| GSE28863_A3 | Up | 0.1387360375 |
| GSE28863_A4 | Up | 0.0636187034 |
| GSE48662 | Up | 0.1078031532 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Guvacine | DB08848 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
