HCSGD entry for SLC6A9
1. General information
| Official gene symbol | SLC6A9 |
|---|---|
| Entrez ID | 6536 |
| Gene full name | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| Other gene symbols | GLYT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003333 | Amino acid transmembrane transport | TAS | biological_process |
| GO:0005283 | Sodium:amino acid symporter activity | IEA | molecular_function |
| GO:0005328 | Neurotransmitter:sodium symporter activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0015187 | Glycine transmembrane transporter activity | IEA | molecular_function |
| GO:0015375 | Glycine:sodium symporter activity | TAS | molecular_function |
| GO:0015672 | Monovalent inorganic cation transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0030001 | Metal ion transport | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902475 | L-alpha-amino acid transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8378597356 | 0.0665989210 | 0.9999902473 | 0.4868885032 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0320016718 |
| GSE13712_SHEAR | Up | 0.1861322916 |
| GSE13712_STATIC | Down | -0.1833091818 |
| GSE19018 | Up | 0.0640463561 |
| GSE19899_A1 | Down | -0.0219093198 |
| GSE19899_A2 | Down | -0.2232934621 |
| PubMed_21979375_A1 | Down | -0.2624844749 |
| PubMed_21979375_A2 | Down | -0.4109569835 |
| GSE35957 | Down | -0.1370569098 |
| GSE36640 | Down | -0.4139578925 |
| GSE54402 | Down | -1.1641514484 |
| GSE9593 | Up | 0.5586060180 |
| GSE43922 | Down | -0.3215804265 |
| GSE24585 | Down | -0.2319918050 |
| GSE37065 | Up | 0.0698685174 |
| GSE28863_A1 | Up | 0.0871848397 |
| GSE28863_A2 | Down | -0.1468820906 |
| GSE28863_A3 | Up | 0.1927842140 |
| GSE28863_A4 | Down | -0.2968537571 |
| GSE48662 | Up | 0.6370274970 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glycine | DB00145 | NUTR00028 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017329 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024167 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025716 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027081 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029053 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
