HCSGD entry for SLC5A5
1. General information
| Official gene symbol | SLC5A5 |
|---|---|
| Entrez ID | 6528 |
| Gene full name | solute carrier family 5 (sodium iodide symporter), member 5 |
| Other gene symbols | NIS TDH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006590 | Thyroid hormone generation | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0008507 | Sodium:iodide symporter activity | IEA | molecular_function |
| GO:0015111 | Iodide transmembrane transporter activity | IMP | molecular_function |
| GO:0015705 | Iodide transport | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | IMP TAS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0071320 | Cellular response to cAMP | IEP | biological_process |
| GO:0071371 | Cellular response to gonadotropin stimulus | IEP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2602984841 | 0.9021205197 | 0.9532299624 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0368619604 |
| GSE13712_SHEAR | Up | 0.1446073118 |
| GSE13712_STATIC | Down | -0.0535232807 |
| GSE19018 | Up | 0.0022024936 |
| GSE19899_A1 | Up | 0.0156800888 |
| GSE19899_A2 | Up | 0.3577249689 |
| PubMed_21979375_A1 | Up | 0.0550084471 |
| PubMed_21979375_A2 | Down | -0.1892794170 |
| GSE35957 | Up | 0.3798693522 |
| GSE36640 | Up | 0.1355727178 |
| GSE54402 | Up | 0.1059220446 |
| GSE9593 | Down | -0.0791973230 |
| GSE43922 | Up | 0.0771339529 |
| GSE24585 | Up | 0.1862062910 |
| GSE37065 | Down | -0.1603776547 |
| GSE28863_A1 | Down | -0.0114391287 |
| GSE28863_A2 | Up | 0.1180776205 |
| GSE28863_A3 | Up | 0.3490592890 |
| GSE28863_A4 | Up | 0.1877448244 |
| GSE48662 | Up | 0.1074616576 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7f-5p | MIMAT0000067 | MIRT032088 | qRT-PCR | Non-Functional MTI (Weak) | 19956384 |
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