HCSGD entry for UBE2Z
1. General information
| Official gene symbol | UBE2Z |
|---|---|
| Entrez ID | 65264 |
| Gene full name | ubiquitin-conjugating enzyme E2Z |
| Other gene symbols | USE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0674984195 | 0.9403222180 | 0.5593321485 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2864537933 |
| GSE13712_SHEAR | Up | 0.3118250354 |
| GSE13712_STATIC | Up | 0.1814744608 |
| GSE19018 | Up | 0.1542287612 |
| GSE19899_A1 | Down | -0.0660784645 |
| GSE19899_A2 | Up | 0.2076467555 |
| PubMed_21979375_A1 | Down | -0.1690340827 |
| PubMed_21979375_A2 | Up | 0.3123768501 |
| GSE35957 | Down | -0.0723970845 |
| GSE36640 | Up | 0.5315659924 |
| GSE54402 | Up | 0.1811951058 |
| GSE9593 | Up | 0.2713837163 |
| GSE43922 | Down | -0.0005745677 |
| GSE24585 | Up | 0.5661830723 |
| GSE37065 | Up | 0.2719170713 |
| GSE28863_A1 | Down | -0.0911417638 |
| GSE28863_A2 | Up | 0.0424106669 |
| GSE28863_A3 | Down | -0.6403418357 |
| GSE28863_A4 | Up | 0.0482062861 |
| GSE48662 | Up | 0.4514230157 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019617 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028379 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041495 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042328 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT043005 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047039 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047448 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047613 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048167 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051172 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
