HCSGD entry for SMTN


1. General information

Official gene symbolSMTN
Entrez ID6525
Gene full namesmoothelin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingTASmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0006939Smooth muscle contractionTASbiological_process
GO:0007517Muscle organ developmentTASbiological_process
GO:0008307Structural constituent of muscleTASmolecular_function
GO:0015629Actin cytoskeletonTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00719357170.91200990460.22113547261.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3282981704
GSE13712_SHEARUp0.2284979167
GSE13712_STATICUp0.1919143032
GSE19018Down-0.2532525342
GSE19899_A1Up0.5568377912
GSE19899_A2Up1.0724440665
PubMed_21979375_A1Up1.3378367665
PubMed_21979375_A2Up1.8724455286
GSE35957Down-0.6909298269
GSE36640Down-0.1172542368
GSE54402Up0.8445990727
GSE9593Down-0.6715090703
GSE43922Up0.6595492259
GSE24585Down-0.0236960246
GSE37065Down-0.0495362813
GSE28863_A1Down-0.0232820676
GSE28863_A2Up0.2020177214
GSE28863_A3Up0.4300741470
GSE28863_A4Up0.1669065773
GSE48662Up0.0796647320

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

27524942Expression of the smooth muscle markers- alpha smooth muscle actin and smoothelin was the highest for cells isolated by enzymatic method I and cultured in SmGM-2
12135889Telomerase-expressing cells contained mRNA for alpha smooth muscle actin, smoothelin, oxytocin receptor, and estrogen receptor alpha, but the estrogen receptor beta receptor was lost
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