HCSGD entry for SLC5A1
1. General information
| Official gene symbol | SLC5A1 |
|---|---|
| Entrez ID | 6523 |
| Gene full name | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| Other gene symbols | D22S675 NAGT SGLT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005412 | Glucose:sodium symporter activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005911 | Cell-cell junction | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0008645 | Hexose transport | TAS | biological_process |
| GO:0015758 | Glucose transport | IMP | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0031526 | Brush border membrane | IEA | cellular_component |
| GO:0034219 | Carbohydrate transmembrane transport | IDA | biological_process |
| GO:0034220 | Ion transmembrane transport | IDA | biological_process |
| GO:0035428 | Hexose transmembrane transport | IDA | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050892 | Intestinal absorption | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7314010410 | 0.8070704570 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0193801016 |
| GSE13712_SHEAR | Down | -0.0491915516 |
| GSE13712_STATIC | Up | 0.0329092186 |
| GSE19018 | Up | 0.0276949391 |
| GSE19899_A1 | Up | 0.0127634084 |
| GSE19899_A2 | Up | 0.2416198512 |
| PubMed_21979375_A1 | Up | 0.2354848667 |
| PubMed_21979375_A2 | Up | 0.0019495341 |
| GSE35957 | Up | 0.1379206742 |
| GSE36640 | Down | -0.0783700160 |
| GSE54402 | Up | 0.1027540620 |
| GSE9593 | Down | -0.0745199041 |
| GSE43922 | Up | 0.0618846730 |
| GSE24585 | Up | 0.0369288698 |
| GSE37065 | Down | -0.0714151331 |
| GSE28863_A1 | Down | -0.0600675110 |
| GSE28863_A2 | Down | -0.0265326710 |
| GSE28863_A3 | Up | 0.1874454108 |
| GSE28863_A4 | Down | -0.0485771776 |
| GSE48662 | Down | -0.1957918471 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Canagliflozin | DB08907 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018696 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
