HCSGD entry for UPF3B

1. General information

Official gene symbolUPF3B
Entrez ID65109
Gene full nameUPF3 regulator of nonsense transcripts homolog B (yeast)
Other gene symbolsHUPF3B MRXS14 RENT3B UPF3X
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIDA IMP NAS TASbiological_process
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003729MRNA bindingIDAmolecular_function
GO:0005487Nucleocytoplasmic transporter activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusNAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIDA NAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:0006406MRNA export from nucleusTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0031124MRNA 3'-end processingTASbiological_process
GO:0035145Exon-exon junction complexIDAcellular_component
GO:0045727Positive regulation of translationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94992420880.06904486530.99999024730.4955820338

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2986307676
GSE13712_SHEARDown-0.0730530958
GSE13712_STATICDown-0.0543252874
GSE19018Down-0.2305435465
GSE19899_A1Down-0.1499243325
GSE19899_A2Down-0.3051635754
PubMed_21979375_A1Down-0.0383337048
PubMed_21979375_A2Down-0.6155315902
GSE35957Down-0.7672116992
GSE36640Down-0.4066248231
GSE54402Down-0.1970078225
GSE9593Down-0.3854647418
GSE43922Down-0.1374922220
GSE24585Up0.1114380298
GSE37065Up0.3387344067
GSE28863_A1Down-0.1071746095
GSE28863_A2Down-0.1669155721
GSE28863_A3Up0.2564826254
GSE28863_A4Up0.0949055139
GSE48662Down-0.4749057088

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029393MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.