HCSGD entry for SLC1A5
1. General information
| Official gene symbol | SLC1A5 |
|---|---|
| Entrez ID | 6510 |
| Gene full name | solute carrier family 1 (neutral amino acid transporter), member 5 |
| Other gene symbols | AAAT ASCT2 ATBO M7V1 M7VS1 R16 RDRC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001618 | Virus receptor activity | IEA | molecular_function |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006860 | Extracellular amino acid transport | IEA | biological_process |
| GO:0006865 | Amino acid transport | TAS | biological_process |
| GO:0006868 | Glutamine transport | TAS | biological_process |
| GO:0015175 | Neutral amino acid transmembrane transporter activity | TAS | molecular_function |
| GO:0015186 | L-glutamine transmembrane transporter activity | TAS | molecular_function |
| GO:0015194 | L-serine transmembrane transporter activity | IEA | molecular_function |
| GO:0015804 | Neutral amino acid transport | TAS | biological_process |
| GO:0016020 | Membrane | IEA TAS | cellular_component |
| GO:0017153 | Sodium:dicarboxylate symporter activity | IEA | molecular_function |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902475 | L-alpha-amino acid transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5950216139 | 0.0099718248 | 0.9999902473 | 0.1980893585 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7640585166 |
| GSE13712_SHEAR | Up | 0.1250839708 |
| GSE13712_STATIC | Down | -0.2341352872 |
| GSE19018 | Up | 0.2270248221 |
| GSE19899_A1 | Down | -0.7882829552 |
| GSE19899_A2 | Down | -0.5365855537 |
| PubMed_21979375_A1 | Up | 1.1011985079 |
| PubMed_21979375_A2 | Down | -0.6620843846 |
| GSE35957 | Down | -0.3274112667 |
| GSE36640 | Down | -0.1524576150 |
| GSE54402 | Down | -0.6897353407 |
| GSE9593 | Up | 0.1963722217 |
| GSE43922 | Up | 0.0517283540 |
| GSE24585 | Down | -0.4742137281 |
| GSE37065 | Down | -0.8363247281 |
| GSE28863_A1 | Up | 0.3868995151 |
| GSE28863_A2 | Down | -0.5933025888 |
| GSE28863_A3 | Down | -0.0430498399 |
| GSE28863_A4 | Down | -0.1350886993 |
| GSE48662 | Up | 0.6461595893 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016308 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020519 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021298 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025224 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031414 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031414 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036461 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042960 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043453 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046514 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21125315 | However, no differences in ASCT2 expression were observed between high and low passage OK cells |
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