HCSGD entry for RAPH1
1. General information
| Official gene symbol | RAPH1 |
|---|---|
| Entrez ID | 65059 |
| Gene full name | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
| Other gene symbols | ALS2CR18 ALS2CR9 LPD PREL-2 PREL2 RMO1 RalGDS/AF-6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007160 | Cell-matrix adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0030175 | Filopodium | IEA | cellular_component |
| GO:0031252 | Cell leading edge | IEA | cellular_component |
| GO:0048675 | Axon extension | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0176049124 | 0.6726901865 | 0.3257398174 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5415178061 |
| GSE13712_SHEAR | Down | -0.1992479995 |
| GSE13712_STATIC | Down | -0.2269479680 |
| GSE19018 | Down | -0.1685357181 |
| GSE19899_A1 | Up | 0.2172587356 |
| GSE19899_A2 | Up | 0.5731364551 |
| PubMed_21979375_A1 | Up | 1.6368378524 |
| PubMed_21979375_A2 | Up | 0.7765994446 |
| GSE35957 | Up | 0.0174479869 |
| GSE36640 | Up | 0.9035082730 |
| GSE54402 | Up | 0.4644858651 |
| GSE9593 | Up | 0.0896767607 |
| GSE43922 | Up | 0.4586904159 |
| GSE24585 | Up | 0.0454131999 |
| GSE37065 | Down | -0.2158797036 |
| GSE28863_A1 | Up | 0.8319499288 |
| GSE28863_A2 | Up | 0.2426387476 |
| GSE28863_A3 | Down | -0.1882859588 |
| GSE28863_A4 | Down | -0.2163597909 |
| GSE48662 | Up | 0.6200260556 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016068 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019271 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030690 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043034 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045080 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045331 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
