HCSGD entry for STIL
1. General information
| Official gene symbol | STIL |
|---|---|
| Entrez ID | 6491 |
| Gene full name | SCL/TAL1 interrupting locus |
| Other gene symbols | MCPH7 SIL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000578 | Embryonic axis specification | ISS | biological_process |
| GO:0001701 | In utero embryonic development | ISS | biological_process |
| GO:0001843 | Neural tube closure | ISS | biological_process |
| GO:0001947 | Heart looping | ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0007224 | Smoothened signaling pathway | ISS | biological_process |
| GO:0007368 | Determination of left/right symmetry | ISS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0021915 | Neural tube development | ISS | biological_process |
| GO:0030900 | Forebrain development | ISS | biological_process |
| GO:0030903 | Notochord development | ISS | biological_process |
| GO:0033504 | Floor plate development | ISS | biological_process |
| GO:0035264 | Multicellular organism growth | ISS | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9729195547 | 0.0001461419 | 0.9999902473 | 0.0213700000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9076323745 |
| GSE13712_SHEAR | Down | -0.0114952803 |
| GSE13712_STATIC | Down | -0.0399080221 |
| GSE19018 | Down | -0.7378763080 |
| GSE19899_A1 | Down | -0.8363200029 |
| GSE19899_A2 | Down | -2.4986041969 |
| PubMed_21979375_A1 | Down | -0.3745615291 |
| PubMed_21979375_A2 | Down | -3.8212067480 |
| GSE35957 | Down | -1.9676308430 |
| GSE36640 | Down | -2.8971002803 |
| GSE54402 | Down | -0.3701242428 |
| GSE9593 | Down | -1.4752556684 |
| GSE43922 | Down | -1.0447202816 |
| GSE24585 | Up | 0.3789708449 |
| GSE37065 | Down | -0.2117400453 |
| GSE28863_A1 | Down | -0.5828258017 |
| GSE28863_A2 | Up | 0.9011139191 |
| GSE28863_A3 | Down | -0.6943422708 |
| GSE28863_A4 | Down | -0.1563090278 |
| GSE48662 | Down | -0.6935323654 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024832 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026496 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029440 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050600 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051025 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
