HCSGD entry for AGXT2
1. General information
| Official gene symbol | AGXT2 |
|---|---|
| Entrez ID | 64902 |
| Gene full name | alanine--glyoxylate aminotransferase 2 |
| Other gene symbols | AGT2 DAIBAT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006206 | Pyrimidine nucleobase metabolic process | TAS | biological_process |
| GO:0008453 | Alanine-glyoxylate transaminase activity | IDA TAS | molecular_function |
| GO:0008483 | Transaminase activity | IEA | molecular_function |
| GO:0009436 | Glyoxylate catabolic process | IDA | biological_process |
| GO:0016223 | Beta-alanine-pyruvate transaminase activity | IEA | molecular_function |
| GO:0019265 | Glycine biosynthetic process, by transamination of glyoxylate | IDA | biological_process |
| GO:0019481 | L-alanine catabolic process, by transamination | IDA | biological_process |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045429 | Positive regulation of nitric oxide biosynthetic process | IDA | biological_process |
| GO:0046135 | Pyrimidine nucleoside catabolic process | TAS | biological_process |
| GO:0046487 | Glyoxylate metabolic process | TAS | biological_process |
| GO:0047305 | (R)-3-amino-2-methylpropionate-pyruvate transaminase activity | IEA | molecular_function |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3696295809 | 0.9051984119 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2231130821 |
| GSE13712_SHEAR | Up | 0.1037938323 |
| GSE13712_STATIC | Up | 0.2014272896 |
| GSE19018 | Up | 0.2082215292 |
| GSE19899_A1 | Up | 0.1433193355 |
| GSE19899_A2 | Up | 0.2820191998 |
| PubMed_21979375_A1 | Up | 0.0695488383 |
| PubMed_21979375_A2 | Down | -0.1882707459 |
| GSE35957 | Up | 0.1084061993 |
| GSE36640 | Up | 0.0474131943 |
| GSE54402 | Up | 0.1016580759 |
| GSE9593 | Down | -0.0145545986 |
| GSE43922 | Up | 0.0138248351 |
| GSE24585 | Down | -0.0854998314 |
| GSE37065 | Up | 0.0102377249 |
| GSE28863_A1 | Down | -0.0980160072 |
| GSE28863_A2 | Down | -0.0052454590 |
| GSE28863_A3 | Up | 0.0729846463 |
| GSE28863_A4 | Up | 0.1731753675 |
| GSE48662 | Down | -0.1382979975 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019037 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
